Publication

128.) Y.-M. Chen, C.-T. Lu, C.-W. Wang, W. B. Fischer;
Repurposing dye ligands as antivirals via a docking approach on viral membrane and globular proteins – SARS-CoV-2 and HPV-16.
Biochim. Biophys. Acta (2024) 1866, 184220 (link)
127.) C.-W. Wang, M.-H. Lin, W. B. Fischer;
Cholesterol affected dynamics of lipids in tailor-made vesicles by ArcVes software during multi micro second coarse-grained molecular dynamics simulations.
AMIS Biophysics (2023) 10, 482-502 (link)
126.) T.-C. Huang, W. B. Fischer;
Predicting the assembly of the transmembrane Domains of viral channel forming proteins and peptide drug screening using a docking approach.
Biomolecules (2022) 12, 1844 (link)
125.) C.-W. Wang, W. B. Fischer;
Rotational dynamics of the transmembrane domains play an important role in peptide dynamics of viral fusion and ion channel forming proteins – a molecular dynamics simulation study.
Viruses (2022) 14, 699 (link)
124.) C.-W. Wang, O. K. Lee, W. B. Fischer;
Screening coronavirus and human proteins for sialic acid binding sites using a docking approach.
AMIS Biophysics (2021) 8, 248-263 (link)
123.) T.-C. Huang, W. B. Fischer;
Sequence – function correlation of the transmembrane domains in NS4B of HCV using a computational approach.
AMIS Biophysics (2021) 8, 165-181 (link)
122.) J. Shaw, R. Gosein, M. M. Kalita, T. L. Foster, J. Kankanala, D. R. Mahato, S. Abas, B. J. King, C. Scott, E. Brown, M. J. Bentham,
L. Wetherill, A. Bloy, A. Samson, M. Harris, J. Mankouri, D. Rowlands, A. Macdonald, A. W. Tarr, W. B. Fischer, R. Foster, S. Griffin;
Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy.
Elife (2020) e52555
121.) Y.-H. Lien, D. R. Mahato, F. Hoppe-Seyler, W. B. Fischer;
Membrane partitioning of peptide aggregates – coarse grained molecular dynamics simulations.
J. Biomol. Struc. Dyn. (2020) 38, 524-532
2014 – 2019
120.) S. Dahl, M. M. Kalita, W. B. Fischer;
Interaction of antivirals with a heptameric bundle model of the p7 protein of hepatitis C virus.
Chem. Biol. Drug Des. (2018) 91, 942-950 (link)
119.) L. Bichmann, Y.-T. Wang, W. B. Fischer;
Corrigendum to “Docking assay of small molecule antivirals to p7 of HCV.” [Comput. Biol. Chem. (2014) 53, 308-317]
Comput. Biol. Chem. (2018) 72, 199
118.) D. R. Mahato, W. B. Fischer;
Specification of binding modes between a transmembrane peptide mimic of ATP6V0C and polytopic E5 of human papillomavirus-16.
J. Biomol. Struc. Dyn. (2017) 36, 2618-2627
117.) M. M. Kalita, W. B. Fischer;
Decoupled side chain and backbone dynamics for proton translocation – M2 of influenza A.
J. Mol. Mod. (2017) 23, 212
116.) J.-H. Lee, C.-F. Hsieh, H.-W. Liu, C.-Y. Chen, S.-C. Wu, T.-W. Chen, C.-S. Hsu, Y.-H. Liao, C.-Y. Yang, J.-F. Shyu, W. B. Fischer, C.-H. Lin;
Lipid rafts-associated stomatin enhances cell fusion.
FASEB J. (2017) 31, 47-59
115.) D. R. Mahato, W. B. Fischer;
Weak selectivity predicted for modeled bundles of the viral channel forming protein E5 of human papillomavirus-16.
J. Phys. Chem. B (2016) 120, 13076-13085
114.) C.-P. Chen, M.-H. Lin, Y.-T. Chan, L.-C. Chen, C. Ma, W. B. Fischer;
Membrane protein assembly: two cytoplasmic phosphorylated serine-sites of Vpu from HIV-1 affect oligomerization.
Sci. Rep. (2016) 6, 28866
113.) N. Laasch, M. M. Kalita, S. Griffin, W. B. Fischer;
Small molecule ligand docking to genotype specific bundle structures of hepatitis C virus (HCV) p7 protein.
Comput. Biol. Chem. (2016) 64, 56-63
112.) M. M. Kalita, W. B. Fischer;
Asymmetric dynamics of ion channel forming proteins – hepatitis C virus (HCV) p7 bundles.
Biochim. Biophys. Acta (2016) 1858, 1462-1470
111.) W. B. Fischer (Editorial);
Classics and hybrids – approaches to modeling the dynamics of biomolecules.
J. Bioanal. Biomed. (2016) 8, e138
110.) M.-H. Lin, C.-P. Chen, W. B. Fischer;
Patch formation of a viral channel forming protein within a lipid membrane – Vpu of HIV-1.
Mol. BioSyst. (2016) 12, 1717-1724
109.) W. B. Fischer, M. M. Kalita, D. Heermann;
Viral Channel forming proteins – how to assemble and depolarize lipid membranes in silico.
Biochim. Biophys. Acta (2016) 1858, 1710-1721
108.) R. Schilling, R. H. A. Fink, W. B. Fischer;
Interaction of ions with the luminal side of the WT and mutated skeletal muscle ryanodine receptor.
J. Mol. Mod. (2016) 22, 37
107.) M.-H. Lin, C. A. Chang, W. B. Fischer;
Estimating binding free energy of a putative growth factors EGF-VEGF complex – a computational bioanalytical study.
J. Biomol. Struc. Dyn. (2016) 34, 1118-1127
106.) J. J. Lin, K. L. Lan, S. F. Chang, Y. F. Chen, W. C. Tsai, P. H. Chiang, M.-H. Lin, W. B. Fischer, Y. S. Shih, S. H. Yen, R. Liu, Y. G. Tsay, H. E. Wang, C. A. Chang;
Development and characterizations of the recombinant human VEGF-EGF dual-targeting fusion protein as a drug delivery system.
Bioconjug. Chem. (2015) 26, 2481-2496
105.) M. M. Kalita, S. Griffin, J. J. Chou, W. B. Fischer;
Genotype-specific differences in structural features of hepatitis C virus (HCV) p7 membrane protein.
Biochim. Biophys. Acta (2015) 1848, 1383-1392 (link)
104.) H.-J. Hsu, M.-H. Lin, C. Schindler, W. B. Fischer;
Structure based computational assessment of channel properties of assembled ORF-8a from SARS-CoV.
Proteins (2015) 83, 300-308
103.) L. Bichmann, Y.-T. Wang, W. B. Fischer;
Docking assay of small molecule antivirals to p7 of HCV.
Comput. Biol. Chem. (2014) 53, 308-317
102.) W. B. Fischer;
Computational chemistry and physics – a world of concepts and anticipations.
The Chemical Axis (2014) 13, No. 2, 1-5
101.) Y.-T. Wang, R. Schilling, R. H. A. Fink, W. B. Fischer;
Ion-dynamics in hepatitis C virus p7 helical transmembrane domains – a molecular dynamics simulation study.
Biophys. Chem. (2014) 192, 33-40
100.) J.-W. Liou, F.-T. Chang, Y. Chung, W.-Y. Chen, W. B. Fischer, H.-J. Hsu;
In silico analysis reveals sequential interactions and protein conformational changes during the binding of chemokine CXCL-8 to its receptor CXCR1.
PLOS One (2014) 9, e94178
99.) M.-H. Lin, H.-J. Hsu, R. Bartenschlager, W. B. Fischer;
Membrane undulation induced by NS4A of Dengue virus – a molecular dynamics simulation study.
J. Biomol. Struc. Dyn. (2014) 32, 1552-1562
98.) W. B. Fischer (Guest-Editor, Special Issue);
Viral Membrane Proteins – Channels for Cellular Networking.
Biochim. Biophys. Acta (2014) 1838, 1057-1198 (link)
97.) W. B. Fischer (Guest-Editor);
Introduction to the Special Issue on ‘Viral Membrane Proteins – Channels for Cellular Networking’.
Biochim. Biophys. Acta (2014) 1838, 1057 (link)
96.) R. Schilling, R. H. A. Fink, W. B. Fischer;
MD simulation of the central pore of ryanodine receptors and sequence comparison with 2B protein from coxsackie virus.
Biochim. Biophys. Acta (2014) 1838, 1122-1131 (link)
95.) W. B. Fischer, L.-H. Li, D. R. Mahato, Y.-T. Wang, C.-P. Chen;
Viral channel proteins in intracellular protein – protein communication: Vpu of HIV-1, E5 of HPV16 and p7 of HCV.
Biochim. Biophys. Acta (2014) 1838, 1113-1121 (link)
94.) L.-H. Li, W. B. Fischer;
Correlation of biological activity with computationally derived structural features from transmembrane hetero-dimers of HIV-1 Vpu with host factors.
Biochim. Biophys. Acta (2014) 1838, 1104-1121 (link)
2008 – 2013
93.) W. B. Fischer (Editorial);
The force field, cachet of structure based computer simulations.
J. Bioanal. Biomed. (2013) 5, e123 (link)
92.) W. B. Fischer, H.-J. Hsu;
From sequence to structure to mechanism – viral channel proteins.
In Sequence and Genome Analysis: Methods and Applications II.; Ed. G. Fung;
i-Concept Books (2013) Chap. 6
91.) L.-H. Li, H.-J. Hsu, W. B. Fischer;
Qualitative computational bioanalytics: Assembly of viral channel-forming peptides around mono and divalent ions.
Biochem. Biophys. Res. Commun. (2013) 442, 85-91 (link)
90.) Y.-T. Wang, H.-J. Hsu, W. B. Fischer;
Computational modeling of the p7 monomer from HCV and its interaction with small molecule drugs.
Springer Plus (2013) 2, 324 (link)
89.) W. B. Fischer (Editorial);
Prospective sciences: computational bioanalytics.
J. Bioanal. Biomed. (2013) 5, e112 (link)
88.) T.-H. Chien, Y.-L. Chiang, C.-P. Chen, P. Henklein, K. Hänel, I.-S. Hwang, D. Willbold, W. B. Fischer;
Assembling an ion channel: ORF 3a from SARS-CoV.
Biopolymers (2013) 99, 628-635 (PDF)
87.) L.-H. Li, H.-J. Hsu, W. B. Fischer;
Assembling viral channel forming proteins: Vpu from HIV-1.
Biopolymers (2013) 99, 517-529 (PDF) (link)
86.) C. Schindler, W. B. Fischer;
Sequence alignment of viral channel proteins with cellular ion channels.
J. Comp. Biol. (2012) 19, 1-13 (PDF) (Suppl.)
85.) W. B. Fischer (Editorial);
Where is Computational Bioanalytics?
J. Bioanal. Biomed. (2012) 4, e104 (link)
84.) K. Wang, W. Lu, J. Chen, S. Xie, H. Shi, H. Hsu, W. Yu, K. Xu, C. Bian, W. B. Fischer, W. Schwarz, L. Feng, B. Sun;
PEDV ORF3 encodes an ion channel protein and regulates virus production.
FEBS Lett. (2012) 586, 384-391 (link)
83.) G.-S. Hong, C.-P. Chen, M.-H. Lin, J. Krüger, C. F. W. Becker, R. H. A. Fink and W. B. Fischer;
Molecular dynamics simulations and conductance studies of the interaction of VP1 from Polio virus and gp41 fusion peptide from HIV-1 with lipid membranes.
Mol. Membr. Biol. (2012) 29, 9-25 (link)
82.) W. B. Fischer, Y.-T. Wang, C. Schindler, C.-P. Chen;
Mechanism of Function of Viral Channel Proteins and implications for drug development.
Int. Rev. Cell Mol. Biol. (2012) 294, 259-321 (PDF)
81.) H.-J. Hsu, W. B. Fischer;
In silico investigations of possible routes of assembly of ORF 3a from SARS-CoV.
J. Mol. Mod. (2012) 18, 501-514 (PDF)
80.) C.-P. Chen, A. Ganguly, C.-Y. Lu, T.-Y. Chen, C.-C. Kuo, R.-S. Chen, W.-H. Tu, W. B. Fischer, K.-H. Chen, L.-C. Chen;
Ultra-sensitive in situ Label-free DNA Detection using GaN Nanowires-based Extended-Gate Field-Effect-Transistor Sensor.
Analyt. Chem. (2011) 83, 1938-1943 (link)
79.) M. Skasko, A. Tokarev, C.-C. Chen, W. B. Fischer, S. K. Pillai, J. Guatelli;
BST-2 is rapidly down-regulated from the cell surface by the HIV-1 protein Vpu: evidence for a post-ER mechanism of Vpu-action.
Virology (2011) 411, 65-77 (PDF)
78.) W. B. Fischer (Guest-Editor, Special Issue)
Viral Ion Channels
Biochim. Biophys. Acta (2011) 1808, 509-588 (link)
77.) W. B. Fischer (Guest-Editor)
Introduction to the Special Issue on viral channel forming proteins.
Biochim. Biophys. Acta (2011) 1808, 509 (link)
76.) C.-C. Chen, J. Krüger, I. Sramala, H.-J. Hsu, P. Henklein, Y.-M. A. Chen, W. B. Fischer;
ORF 8a of SARS-CoV forms an ion channel: experiments and molecular dynamics simulations.
Biochim. Biophys. Acta (2011) 1808, 572-579 (PDF)
75.) W. B. Fischer and H.-J. Hsu;
Viral channel forming proteins – modelling the target.
Biochim. Biophys. Acta (2011) 1808, 561-571 (link)
74.) G. Patargias, G. Ewart, C. Luscombe, W. B. Fischer;
Ligand-protein docking studies of potential HIV-1 drug compounds using the algorithm FlexX.
Anal. Bioanal. Chem. (2010) 396, 2559-2563 (PDF)
73.) W. B. Fischer (Guest-Editor, Special Issue)
Viral Membrane Proteins Meeting held in Heidelberg, December 2008
Eur. Biophys. J. (2010) 39, 1041-1104 (link)
72.) W. B. Fischer, G. Thiel, R. H. A. Fink;
Viral membrane proteins.
Eur. Biophys. J. (2010) 39, 1041-1042 (PDF)
71.) C.-P. Chen, C. Kremer, P. Henklein, U. Schubert, R. H. A. Fink, W. B. Fischer;
Modulating the activity of the channel forming segment of Vpr protein from HIV-1.
Eur. Biophys. J. (2010), 39, 1089-1095 (PDF)
70.) J. Krüger, W. B. Fischer;
Structural implications of mutations assessed by molecular dynamics: Vpu1-32 from HIV-1.
Eur. Biophys. J. (2010), 39, 1069-1077 (PDF)
69.) J. Krüger, W. B. Fischer;
Assembly of viral membrane proteins.
J. Chem. Theory Comput. (2009) 5, 2503-2513 (link)
68.) G. Patargias, T. Barke, A. Watts, W. B. Fischer;
Model generation of viral channel forming 2B protein bundles from polio and coxsackie viruses.
Mol. Membr. Biol. (2009) 26, 1-13 (PDF)
67.) G. Patargias, H. Martay, W. B. Fischer;
Reconstructing potentials of mean force from short steered molecular dynamics simulations of Vpu from HIV-1.
J. Biomol. Struc. Dyn. (2009) 26, 1-12 (link)
66.) K. Tiewsiri, W. B. Fischer, C. Angsuthanasombat;
Lipid-induced conformation of helix 7 from the pore-forming domain of the Bacillus thuringiensis Cry4Ba toxin: implications for the toxicity mechanism.
Arch. Biochem. Biophys. (2009) 482, 17-24 (PDF)
65.) W. B. Fischer, J. Krüger;
Viral channel forming proteins.
Int. Rev. Cell Mol. Biol. (2009) 275, 35-63 (PDF)
64.) G. Patargias, H. Martay, J. Krüger, C.-P. Chen, Y.-T. Wang, M.-D. Lee, C.-C. Chen, G.-S. Hong, W. B. Fischer;
Short membrane proteins from viruses: channel-pore dualism?
Proceedings From Computational Biophysics to Systems Biology 2008, Jülich, D. (PDF)
63.) J. Krüger, W. B. Fischer;
Viral membrane proteins: flexibility and assembly.
Proceedings From Computational Biophysics to Systems Biology 2008, Jülich, D. (PDF)
62.) J. Krüger, W. B. Fischer;
Exploring the conformational space of Vpu from HIV-1: a versatile adaptable protein.
J. Comput. Chem. (2008) 29, 2416-2424 (PDF)
61.) T. Mehnert, A. Routh, P. J. Judge, Y. M. Lam, D. Fischer, A. Watts, W. B. Fischer;
Biophysical characterisation of Vpu from HIV-1 suggests a channel-pore dualism.
Proteins (2008) 70, 1488-1497 (PDF)
60.) J. Krüger, G. Patargias, H. Martay, T. Mehnert, A. Routh, P. J. Judge, Y. H. Lam, D. Fischer, A. Watts, W. B. Fischer;
Self- Assembly of viral ion channel forming proteins.
Proceedings of the IX. Linz Winter Workshop 2007, (2008) 31-35, TRAUNER Druck, Linz, AT ISBN 978-3-85499-400-8 (PDF)
2002 – 2007
59.) T. Mehnert, Y. H. Lam, P. J. Judge, A. Routh, D. Fischer, A. Watts, W. B. Fischer;
Towards a mechanism of function of the viral ion channel Vpu from HIV-1.
J. Biomol. Struc. Dyn. (2007) 24, 589-596 (PDF)
58.) C. G. Kim, V. Lemaitre, A. Watts, W. B. Fischer;
Drug-protein interaction with Vpu from HIV-1: proposing binding sites for amiloride and one of its derivatives.
Anal. Bioanal. Chem. (2006) 386, 2213-2217 (PDF)
57.) V. Lemaitre, D. Willbold, A. Watts, W. B. Fischer;
Full length Vpu from HIV-1: combining molecular dynamics simulations with NMR spectroscopy.
J. Biomol. Struc. Dyn. (2006) 5, 485-496 (link)
56.) G. Patargias, N. Zitzmann, R. Dwek, W. B. Fischer;
Protein-protein interactions: modeling the hepatitis C virus ion channel p7.
J. Med. Chem. (2006) 49, 648-655 (PDF)
55.) W. B. Fischer;
Virale Ionenkanäle: Bildung, Modelling, Drug Targeting.
Nachr. Chem. (2005) 53, 1216-1221 (PDF)
54.) A. Candler, M. Featherstone, R. Ali, L. Maloney, A. Watts, W. B. Fischer;
Computational analysis of mutations in the transmembrane region of Vpu from HIV-1.
Biochim. Biophys. Acta-Biomembr. (2005) 1716, 1-10 (PDF)
53.) D. Pavlovic, W. Fischer, M. Hussey, D. Durantel, S. Durantel, N. Branza-Nichita, S. Woodhouse, R. Dwek, N. Zitzmann;
Long alkylchain iminosugars block the HCV p7 ion channel.
Adv. Exp. Med. Biol. (2005) 564, 3-4
52.) W. B. Fischer, P. J. Judge;
Viral Ion Channels.
BioForum Europe (2005) 4, 45-47 (PDF)
51.) W. B. Fischer; (Book Editor)
Viral Membrane Proteins: Structure, Function and Drug Design.
Vol. 1, Kluwer Academic / Plenum Publisher, New York, (2005) ISBN 978-0-306-48495-7 (link)
50.) V. Lemaitre, C. G. Kim, D. Fischer, Y. H. Lam, A. Watts, W. B. Fischer;
Defining drug interactions with the Vpu ion channel from HIV-1.
In: Viral Membrane Proteins: Structure, Function and Drug Design. (W. B. Fischer, Ed.)
Z. Atassi, Serial Ed., Protein Reviews; Kluwer Academic / Plenum Publishers New York (2005) Chap. 14, 187-205
49.) W. B. Fischer, Y. H. Lam, A. D. Ward;
Peptide containing vesicles trapped with Raman tweezers – Vpu1-32 from HIV1.
Annual Report of the CCLRC Rutherford Appleton Laboratory, Didcot, (2004/05) (PDF)
48.) W. Römer, Y. H. Lam, D. Fischer, A. Watts, W. B. Fischer, P Göring, R. B. Wehrspohn, U. Gösele, C. Steinem;
Channel activity of a viral transmembrane peptide in micro-BLMs: Vpu1-32 from HIV-1.
J. Am. Chem. Soc. (2004) 126, 16267-16274 (PDF)
47.) V. Lemaitre, R. Ali, C. G. Kim, A. Watts, W. B. Fischer;
Interaction of amiloride and one of its derivatives with Vpu from HIV-1: a molecular dynamics simulation.
FEBS Lett. (2004) 563, 75-81 (PDF)
46.) W. B. Fischer [Review]
Vpu from HIV-1 on an atomic scale: experiments and computer simulations.
FEBS Lett. (2003) 552, 39-46 (PDF)
45.) D. Pavlovic, D. C. A. Neville, O. Argaud, B. Blumberg, R. A. Dwek, W. B. Fischer, N. Zitzmann;
The hepatitis C virus p7 protein forms an ion channel which is inhibited by long alkylchain iminosugar derivatives.
Proc. Natl. Acad. Sci. USA (2003) 100, 6104-6108 (PDF)
44.) I. Sramala, V. Lemaitre, J. D. Faraldo-Gómez, S. Vincent, A. Watts, W. B. Fischer;
Molecular dynamics simulations on the first two helices of Vpu from HIV-1.
Biophys. J. (2003) 84, 3276-3284 (PDF)
43.) W. B. Fischer [Trends];
Computational bioanalysis of proteins.
Anal. Bioanal. Chem. (2003) 375, 23-25 (PDF)
42.) F. S. Cordes, A. D. Tustian, M. S. P. Sansom, A. Watts, W. B. Fischer;
Bundles consisting of extended transmembrane segments of Vpu from HIV-1: computer simulations and conductance measurements.
Biochemistry (2002), 41, 7359-7365 (PDF)
41.) W. B. Fischer, M. S. P. Sansom [Review];
Viral ion channels: structure and function.
Biochim. Biophys. Acta (2002), 1561, 27-45 (PDF)
40.) W. B. Fischer, M. S. P. Sansom;
Probing the structure of viral ion channel proteins: a computational approach.
in ‘Biophysical Chemistry. Membranes and Proteins’
Eds. R. H. Templer, R. Leatherbarrow, Royal Soc. Chemistry 2002
1996 – 2001
39.) W. B. Fischer, M. Pitkeathly, B. A. Wallace, M. S. P. Sansom;
Transmembrane peptides for applications in biosensors: NB from influenza B.
Proceedings contribution (10 pages) to ‘BioSensor 2001’, Tuebingen, D (PDF)
38.) F. S. Cordes, A. Kukol, L. R. Forrest, I. T. Arkin, M. S. P. Sansom, W. B. Fischer;
The structure of the HIV-1 Vpu ion channel: modelling and simulation studies.
Biochim. Biophys. Acta (2001), 1512, 291-298 (PDF)
37.) A. J. Wright, S. E. Matthews, W. B. Fischer, P. D. Beer;
Novel resorcin[4]arenes as potassium selective ion channel and transporter mimics.
Chem. Eur. J. (2001), 7, 3474-3481 (PDF)
36.) W. B. Fischer, M. Pitkeathly, M. S. P. Sansom;
Amantadine blocks channel activity of the transmembrane segment of the NB protein from influenza B.
Eur. Biophys. J. (2001), 30, 416-420 (PDF)
35.) W. B. Fischer, A. Fedorowicz, A. Koll;
Structural water around ions – FTIR difference spectroscopy and quantum-mechanical calculations.
Phys. Chem. Chem. Phys. (2001), 3, 4228-4234
34.) W. B. Fischer, G. Steiner, C. Kuhne, R. Salzer;
Investigation on native vesicles containing the nicotinic acetylcholine receptor using FTIR-spectroscopy.
J. Mol. Struc. (2001), 570, 153-158 (PDF)
33.) W. B. Fischer, M. Pitkeathly, B. A. Wallace, L. R. Forrest, G. R. Smith, and M. S. P. Sansom;
Transmembrane peptide NB of influenza B: a simulation, structure, and conductance study.
Biochemistry (2000), 39, 12708-12716 (PDF)
32.) W. B. Fischer, L. R. Forrest, G. R. Smith, and M. S. P. Sansom;
Transmembrane domains of viral ion channel proteins: a molecular dynamics simulation study.
Biopolymers (2000), 53, 529-538 (PDF)
31.) W. B. Fischer, D. Schwenke, B. Leupold, S. Friedrich, G. Steiner, R. Salzer;
Sensing local anaesthetics with nicotinic acetylcholine receptor rich vesicles in solution – A fluorescence study.
Asian Chem. Lett. (2000), 4, 57-64
30.) R. Salzer, G. Steiner, S. Friedrich, Ch. Kuhne, W. Fischer;
Functional biomembranes for sensors.
Infrared Sensors & Systems, AMA Service Wunstorf (2000) 7-12
29.) G. Steiner, W. Fischer, Ch. Kuhne, and R. Salzer;
Surface enhanced FTIR spectroscopy and surface plasmon resonance on Biomembranes.
Proceed SPIE (2000), 3918, 215-221
28.) Liu X., Lee M. J., Coleman M., Rath P., Nilsson A., Fischer W. B., Bizounok M., Herzfeld J., Karstens W. F. J., Raap J., Lugtenburg J., and Rothschild K. J.;
Detection of threonine structural changes upon formation of the M-intermediate of bacteriorhodopsin: evidence for assignment to Thr-89.
Biochim. Biophys. Acta (1998), 1365, 363-372 (PDF)
27.) W. B. Fischer, I. Unverricht, T. Dudev, R. Salzer;
Negative ions causing structural changes of the acetylcholine cation – FTIR-spectroscopy and theoretical calculations.
Asian J. Spectrosc. (1998), 2, 125-130
26.) I. Unverricht, W. B. Fischer, A. Schrattenholz, A. Maelicke, R. Salzer;
FTIR-Spektroskopische Charakterisierung von Self Assembly Schichten mit Ionenkanälen.
Chemie- und Biosensoren: aktuelle Anwendungen und Entwicklungstrends; Eds.: J. P. Baselt, G. Gerlach, W. Göpel;
Dresden University Press (1998), 31-34
25.) R. Salzer, C. Kuhne, G. Steiner, and W. B. Fischer;
Investigation of functionalized biomembranes by ATR-SEIRA spectroscopy with polarized light.
Proceed. SPIE (1998), 3250, 96-100
24.) Ch. Kuhne, G. Steiner, W. B. Fischer, R. Salzer;
Surface enhanced FTIR spectroscopy on membranes.
Fres. J. Anal. Chem. (1998), 360, 750-754.
23.) G. Steiner, C. Kuhne, B. Leupolt, W. B. Fischer, and R. Salzer;
Applications of surface enhanced spectroscopic techniques to biosystems.
Proceed. SPIE (1998), 3256, 106-112
22.) R. Salzer, W. B. Fischer, I. Unverricht, D. Schwenke, G. Steiner, A. Schrattenholz, and A. Maelicke;
Spectroscopic investigation of nicotinic acetylcholine receptor for application in medical diagnosis.
Proceed. SPIE (1998), 3257, 288-295
21.) C. Kuhne, G. Steiner, W. B. Fischer, and R. Salzer;
SEIRA Spectroscopy on Biomembranes.
Conf. Proceed. API Press (1998), 430, 606-609
20.) W. B. Fischer, I. Unverricht, Ch. Kuhne, G. Steiner, A. Schrattenholz, A. Maelicke, and R. Salzer;
Vesicles containing ion channels on crystalline surfaces – An FTIR and Surface Enhanced FTIR Spectroscopic study.
Conf. Proceed. API Press (1998), 430, 594-597
19.) W. B. Fischer, P. Pötschke, G. Pompe, K.-J. Eichhorn, and H. W. Siesler;
Rheo-Optical Fourier transform infrared spectroscopy of polyurethanes and their blends with polyolefines.
Macromolecular Chemistry and Physics (1997), 198, 2057-2072
18.) W. B. Fischer, P. Pötschke, K.-J. Eichhorn and H.W. Siesler;
Rheo-optical FTIR-spectroscopy of polyurethane-polyolefine-blends during cyclic elongation and recovery.
Microchim. Acta [Suppl.] (1997), 14, 411-412
17.) W. B. Fischer, I. Fischer, and R. Salzer;
Investigation of acetylcholine under the influence of different electrostatic fields by FTIR difference spectroscopy.
Microchim. Acta [Suppl.] (1997), 14, 441-443
16.) W. B. Fischer, P. Wu, U. Hoffmann, K.-J. Eichhorn, H. W. Siesler, and K. J. Rothschild;
Comparison of bacteriorhodopsin conformational changes with uniaxially elongated aliphatic polyamide samples using FTIR difference spectroscopy.
Microchim. Acta [Suppl.] (1997), 14, 437-439
15.) W. B. Fischer, and H.-H. Eysel;
Raman- and FTIR spectroscopic study on water structural changes in aqueous solutions of amino acids and related compounds.
J. Mol. Struc. (1997), 415, 249-257
14.) W. B. Fischer, I. Unverricht, D. Schwenke, G. Steiner, P. Nollert, A. Schrattenholz, A. Maelicke, and R. Salzer;
Adsorption of functionalized biomembrane vesicles on crystalline surfaces monitored by FTIR- and Surface Enhanced FTIR Spectroscopy.
In: Carmona P., Navarro R., Hernanz A. (eds) Spectroscopy of Biological Molecules: Modern Trends. Springer, Dordrecht, pp 301-302
13.) R. Salzer, W. Fischer, and G. Steiner;
Ionenkanäle als Signalbausteine.
CLB Chemie in Labor und Biotechnik 47, (1996), 7, 305-311
1989 – 1995
12.) W. B. Fischer, I. Fischer, G. Steiner, A. Schrattenholz, A. Maelicke, R. Salzer;
Structural analysis of the nicotinic-acetylcholine receptor immobilized on crystals and phospholipids studied by FTIR-spectroscopy.
1st Int. Symp. Bioanal. Chem. Proc., Chinese Chem. Soc., Beijing, Peop. Rep. China (1995), 16-17
11.) W. B. Fischer, S. Sonar, T. Marti, H. G. Khorana and K. J. Rothschild;
Detection of a water molecule in the active-Site of bacteriorhodopsin; Hydrogen bonding changes during the primary photoreaction.
Biochemistry (1994), 33, 12757-12762
10.) S. Sonar, T. Marti, P. Rath, W. Fischer, M. Coleman, A. Nilsson, H. G. Khorana and K. J. Rothschild;
A redirected proton pathway in the bacteriorhodopsin mutant Y57D.
J. Biol. Chem. (1994), 269, 28851-28858
9.) W. Fischer, H. H. Eysel, O. F. Nielsen, J. E. Bertie;
Corrections to the baseline distortions in the OH-stretch region of aqueous solutions.
Appl. Spectroscopy (1994), 48, 107-112
8.) W. B. Fischer and K. J. Rothschild;
Water molecules are active during the primary photoreaktion of bacteriorhodopsin.
SPIE Vol. (1993), 2089, 118-119
7.) S. Sonar, N. Patel, W. Fischer and K. J. Rothschild;
Cell-Free synthesis, functional refolding, and spectroscopic characterization of bacteriorhodopsin, an integral membrane protein.
Biochemistry (1993), 32, 13777-13781
6.) K. J. Rothschild, T. Marti, S. Sonar, Y.-W. He, P. Rath, W. Fischer, O. Bousché and H. G. Khorana;
Asp96 Deprotonation and transmembrane a -helical structural changes in bacteriorhodopsin.
J. Biol. Chem. (1993), 268, 27046-27052
5.) Y.-W. He, M. P. Krebs, W. B. Fischer, H. G. Khorana, K. J. Rothschild;
FTIR Difference spectroscopy of the bacteriorhodopsin mutant Tyr-185 to Phe: Detection of a stable O-like species and characterization of its photocycle at low temperature.
Biochemistry (1993), 32, 2282-2290
4.) W. B. Fischer, H. H. Eysel;
Polarized Raman spectra and intensities of aromatic amino acids phenylalanine, tyrosine and tryptophan.
Spectrochimica Acta (1992), 48A, 725-732
3.) W. B. Fischer, J. E. Bertie, M. Khalique Ahmed, H. H. Eysel;
The influence of aliphatic amines and carboxylic acids on the water structure studied by vibrational spectra of solutions.
in Proceedings of the 8th International Conference on Fourier Transform Spectroscopy 1991,
Lübeck-Travemünde, Deutschland, SPIE Vol. (1991), 1575, 596-597
2.) H. H. Eysel, W. Fischer;
pH-Dependence of characteristic Raman bands of aromatic amino acids in Spectroscopy of Biological Molecules – State of the Art.
Proceedings of Third European Conference on the Spectroscopy of Biological Molecules, Societa Editrice Esculapio Bologna, Italy (1989), Editors A. Bertoluzza, C. Fagnano, P. Monti, 87-88
1.) M. E. Maxon, B. Redfield, X. Cai, R. Shoeman, K. Fujita, W. Fisher, G. Staufer, H. Weissbach, N. Brot;
Regulation of methionine synthesis in Escherichia coli: Effect of the MetR protein on the expression of the metE and metR genes.
Proc. Natl. Acad. Sci. USA (1989), 86, 85-89